联系方式
邮箱：liucp74@hotmail.com
个人简介
1993-1997年：吉林大学理学学士（Jilin University, B.Sc.）
1997-2000年：吉林大学理学硕士（Jilin University, M.Sc）
2000-2004年：中科院生物物理研究所理学博士（Institute of Biophysics, CAS, Ph.D.）
2005-2007年：宾西法尼亚大学理学博士后（University of Pennsylvania, Postdoc）
2008-2021年：hg6686体育平台理学副教授（Harbin Institute of Technology, Assoc. Prof.）
研究方向和领域
分子伴侣
Chaperone
酶学
Enzymology
研究内容
分子伴侣构效关系以及对蛋白内稳态的影响作用机制；蛋白修饰酶生理功能及其抑制剂开发
The relationship of structure and function of chaperones and their roles in proteostasis maintenance;the physiological roles of protein modifiers and their inhibitor
研究成果
1.**Zhongya Sun#; Hao Zhang#; Yuanyuan Zhang#; Liping Liao#; Wen Zhou#; Fengcai Zhang; Fulin Lian; Jing Huang; Pan Xu; Rukang Zhang; Wenchao Lu; Mingrui Zhu; Hongru Tao; Feng Yang; Hong Ding; Shijie Chen; Liyan Yue; Bing Zhou; Naixia Zhang; Minjia Tan; Hualiang Jiang; Kaixian Chen; Bo Liu*; Chuanpeng Liu*; Yongjun Dang*; Cheng Luo*; Covalent inhibitors allosterically block the activation of Rho family proteins and suppress cancer cell invasion, Advanced Science,2020, 7(14): 2000098
2.Feng-cai Zhang#; Zhong-ya Sun#; Li-ping Liao; Yu Zuo; Dan Zhang; Jun; Wang; Yan-tao Chen; Sen-hao Xiao; Hao Jiang; Tian Lu; Pan Xu; Li-yan Yue; Dao-hai Du; Hao Zhang; Chuan-peng Liu*; Cheng Luo*; Discovery of novel CBP. bromodomain inhibitors through TR-FRET-based high-throughput screening, acta pharmacologica sinica, 2020, 41(2): 286-292.
3.**Dongjie Fan, Shunan Cao, Qiming Zhou, You Zhang, Lei Yue, Chang Han, Bo Yang, Yu Wang, Zhuo Ma, Lingxiang Zhu, Chuanpeng Liu;Exploring the roles of substrate-binding surface of chaperone site in the chaperone activity of trigger factor;The FASEB Journal; 2018, 32(12): 6655-6665
4.Dongjie Fan, Lushan Liu, Lingxiang Zhu, Fang Peng, Qiming Zhou*, Chuanpeng Liu*. (2017) Global Analysis of the Impact of Deleting Trigger Factor on the Transcriptome Profile of Escherichia coli，J.Cell. Biochem. 118(1): 141-153
5.Dongjie Fan, Chuanpeng Liu*, Lushan Liu, Lingxiang Zhu, Fang Peng, Qiming Zhou*. (2016) Large-scale gene expression profiling reveals physiological response to deletion of chaperone dnaKJ in Escherichia coli. Microbiol. Res. 186-187: 27-36
开设的课程
分子生物学
Molecular Biology
生物大分子结构与功能
Structure and Function of Biomacromolecule
分子生物学进展
Progress in Molecular Biology
教师个人主页链接
http://homepage.hit.edu.cn/liuchuanpeng
