Tag Archives: cannabinoids

Forensic Testing using THC:CBD

pisstified

With the adoption of the United Nation’s Single Convention on Drug Control in 1971, it became necessary for the international forensic community to be able to differentiate “drug-type” cannabis from “fiber-type”.

Due to the restricted research and limited knowledge of cannabis at the time, the United Nations adopted and recommended the ratio of the two main constituents of cannabis -THC and CBD .  In other words, if the ratio of THC:CBD was greater than 1 – it was deemed a drug; if the ratio was less than one, the plant was deemed to be hemp.

Cannabis is finally being accepted as the medicinal plant it is and as countries move towards accepting recreational cannabis, why is the industry still only focused on the ratio of THC to CBD????

To emphasize the meaningless of the THC to CBD ratio, the following strain fingerprints are for your perusal:

Durban poison
Pure Sativa – uplifting and ability to focus, it relieves stress, fatigue, depression
la con 2
Indica – calming  – relieves stress, insomnia, depression
acdc 2
Sativa dominant – focused and energizing, it relieves seizures, stress, inflammation and pain
Sour Diesel 2
Sativa dominant – energizing – relieves stress, depression and pain

With the exception of the ACDC strain above, the cannabinoid – CBD (cannabidiol) is only present in trace amounts in the above strain fingerprints, relative to CBG, CBC and or THCV.

The above strain fingerprints not only disclose the major cannabinoids present in a given strain, it also discloses the terpenes that are present.  Terpenes and cannabinoids are produced in the heads of the glandular trichomes, produced during the flowering stage of unfertilized female plants.

For indepth research on cannabinoids and terpenes, the following e-book is available at Amazon  and provides indepth information on cannabinoids, terpenes, strain fingerprints, plus so much more.

cannabis medicine
e-book link here

The synergistic benefits of the plant’s naturally produced cannabinoids and terpenes provide a great deal of additional benefits relative to just THC or CBD. As consumers and patients of cannabis become more educated on the full potential of this plant, it is important to insist on reviewing the full strain footprint from licensed vendors. In this way, the quality of product should increase, along with indepth research on the medicinal qualities of this plant.

Cannabis Control

ask ur doc

How is it that society is better off when its constituents are worse off? Herein lies the hypocrisy with cannabis prohibition.

 The health benefits of cannabis are astounding and miraculous. Research on the medical benefits of cannabis can be found here; here and here – for starters. The latter link is the number of patent applications filed on cannabinoids by GW Pharma in the UK and the NIH in the US – the only ones allowed access to research and control.

The Antique Cannabis Book has uncovered incriminating evidence against the UN in that the government has known, since the forties, the miraculous epilepsy cure that cannabis provides to those patients.

Who is the UN and how did it come to be? Check this link here

Society is actually defined as those whom control the people. The fallacy is, the people ultimately have control!

Stand up and fight for your rights!

Synthetic THC to treat Cannabis Use Disorder???

huh

According to ClinicalTrials.gov Nabilone is being used in “clinical trials” as a cure for “cannabis use disorder”. (RUFKM)?

Nabilone, (a.k.a. Cesamet owned by Valeant Pharma)  is a synthetic or lab made form of the cannabinoid THC (delta-9-tetrahydrocannabinol), the active ingredient in cannabis. Coincidentally, this lab based form resembles the street based synthetic THC known as “spice”or “K2” and is being sold as an incense. K2 or Spice is NOT a natural form of anything, least of all, cannabis. Anything made in a lab, such as spice/k2 is dangerous.

The scientist credited with manufacturing synthetic THC in a lab is – John W Hoffman, PhD,  a retired Clemson University chemist whose initials, JWH, is linked with the synthetic cannabinoid JWH-018, a.k.a. Spice.

It should be noted that in 2007, Valeant Pharma acquired the commercial rights to nabilone in the United Kingdom and other EU markets at a cost of $14 million. http://www.businesswire.com/news/home/20070215005880/en/Valeant-Pharmaceuticals-Acquires-Rights-Nabilone-United-Kingdom

“The DSM – (Diagnostic and Statistical Manual of Mental Disorders) is said to be the standard classification of mental disorders used for clinical, research, policy, and reimbursement purposes in the United States and elsewhere. It therefore has widespread importance and influence on how disorders are diagnosed, treated, and investigated. Since its first publication in 1952, DSM has been reviewed and revised four times; the criteria in the last version, DSM-IV-TR, were first published in 1994. Since then, knowledge about psychiatric disorders, including substance use disorders, has advanced greatly. To take the advances into account, a new version, DSM-5, was published in 2013.”  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767415/

Has CBC been misinterpreted as CBD as a result of Gas Chromatography?

cbc

With all the hype about the cannabinoid – CBD or Cannabidiol, would it come as a surprise to learn that those in control, have made a very important error?

In the US, the federal government has historically emphasized and funded only research on the potential harm associated with “marijuana” use. In fact, from 2008-2014, the National Institute of Health (NIH) spent an estimated $1.1 BILLION on marijuana research that emphasized abuse and addiction. Yet, the US government has routinely and consistently filed patent applications on every health benefit that cannabis possesses.

The US government (DEA, NIH, etc) determined that gas chromatography was a useful and  objective method for separating cannabinoids in a sample to determine its potency. In addition, since their scientists determined that the only other important cannabinoid worth studying was CBD or cannabidiol, they have misled the virgin cannabis patients with their faulty information.

New information obtained from reliable sources show that using gas chromatography can incorrectly show CBC as CBD (cannabichromene as cannabidiol)!!!

http://blog.restek.com/?p=8759

To further your understanding about cannabinoids in cannabis as well as the different chromatography testing methods that can identify the cannabinoids in your medicine, please click the following book image:

Cannabinoids cover
Click on image

Cannabinoids for Pain

same indica but almost harvest

GW Pharma Limited (United Kingdom) and Otsuka Pharmaceutical Co. Limited (Japan) have filed an International Patent Application for specific “Cannabinoids for the Treatment of Neuropathic Pain”!

The English Abstract is as follows:

“The present invention relates to cannabinoids for use in the treatment of neuropathic pain. Preferably the cannabinoids are one or more phytocannabinoids of: cannabigerol (CBG), cannabichromene (CBC), cannabidivarin (CBDV) or tetrahydrocannabivarin (THCV). More preferably the phytocannabinoids are isolated and / or purified from cannabis plant extracts.”

This patent claims that it is a novel discovery, however, in the book “Cannabinoids and Terpenes: The Medicinal Benefits of Cannabis“, Ryder Management along with many other patients of medical cannabis, have known this for years.

Profits before Patients and the duplicity of Health Canada

Thanks to Rick Simpson, I now have a profound respect and understanding of the cannabis plant. In addition to many hours devoted to researching the history of this plant, along with testing various strains using a thin layer chromatography (TLC) kit, I am appalled and somewhat frustrated with how Health Canada seems to think that they can insist patients needing medical cannabis will simply rollover and buy cannabis where they dictate. In other words, Ontario needs to take a lesson from those in BC. Stand up and fight for your rights!

Although the constitutional challenge over the right to grow our own plant medicine is presently undecided and therefore, no law presently exists, if our right to grow is taken away, patients will be denied the right to juice this medicinal plant!

Indica Skunk with THC, CBG (Cannabigerol) and THCV (tetrahydrocannabivarin) as dominant cannabinoids

young indicala con 2indica 4 cropped

It might come as a surprise to many that contrary to the literature, many indica skunk strains we tested, show a higher ratio of the cannabinoids CBG and THCV over the much touted CBD cannabinoid.

What does this mean?

As medical cannabis patients, we must become more discerning and particular when choosing the specific strain of medical cannabis that works best for our individual and unique needs.

The cannabinoids in cannabis work in a synergistic capacity and we should not accept a simplistic standardization that, although facilitates the pharmaceutical industry’s method of monopolistic distribution, ultimately limits what this plant could otherwise offer us in terms of full homeostasis.

In Canada, the ministry that thinks they own our health, has basically handed control of the cannabis plant over to corporate bankers. These suits who were promised a large return on investment, are allowed to use approved pesticides on a plant that was previously grown organically by most approved growers under the old system.

Furthermore, the new licensed growers/producers are also only required to disclose the percentage of only the THC and CBD cannabinoid content, as if those are the only two cannabinoids that exist.

Other Countries have a misconception that Canada is advanced with their new MMPR legislation. Nothing can be further from the truth. Health Canada is selling the patients who need the medicine to big corp who only want to make money through control. Without the right to grow, patients will lose their right to juice, a life saving remedy for numerous disorders.

Cannabigerol (CBG) versus Cannabidiol (CBD)

Cannabinoids cover

In the above book “Cannabinoids and Terpenes“, the writer used “thin layer chromatography” (TLC) to identify the cannabinoids in the indica  strains used to make “Rick Simpson Oil” (using grain alcohol) to treat terminal liver cancer.

Surprisingly, where the author expected to see CBD on the test plates, the TLC organic chemistry test kit plates, or chromatograms, identified no CBD BUT did show CBG, THCV and of course THC.

The DEA has used thin layer chromatography as a method of identifying where the cannabis confiscated originated from.

It should be noted that up until recently, the literature on cannabinoids reported that strains with no CBD but high indications of CBG are classified as hemp plants.

In trying to obtain the truth on health remedies, it does become frustrating when the government whom we rely on for truth, report contradicting information from that which one discovers solely from the pursuit of knowledge and truth.

Genetically Modified Pot?

MMAR home grown
homegrown

Under the MMAR (Canada’s old Marijuana for Medical Purposes Regulations), it allowed patients in Canada to choose their medicine. After all, are we not masters of our own domain? Able to determine what our body needs? When did we give that up, if we did?

The above “thin layer chromatography” (TLC) chromatogram (a.k.a. bud footprint) clearly identifies more than just THC in three bud samples tested  (including a sample of BC Bud). These are buds grown under the MMAR regulations, when patients in Canada had a choice and could choose their medicine.

Compare being Masters of our own Domain, above,  with what Health Canada has regulated, below:

LP pot
LP pot

LP Pot (pot from Licensed Producers), is the second chromatogram and shows three samples from Licensed Producers’ pot, under the MMPR. Please take a minute to compare the two chromatograms, both shown above.

LP pot, second example, only shows THC and in a very strange way. Genetically altered?

The question that needs an answer is this:

Are patients in Canada guaranteed that the Health Minister has not again sold out out health to genetically altered cannabis cultivars to and from Big Pharma?

Liver Cancer in Adults and Cannabinoids

not just for hippies

Hepatocellular carcinoma (HCC), also known as liver cancer,  is reported to have a high mortality rate and has no adequate treatment. However, Allopathic Practitioners still use their “cut, poison and burn” methods of medical care.

Fortunately, thanks to the many proponents of natural health, science has recently disclosed their discovery of our endogenous cannabinoid system and how we all carry cannabinoid receptors  (the endogenous cannabinoid system is also called the endocannabinoid system for short). In addition, the phytocannabinoids that are unique to the cannabis plant, have the ability of using the signals of our cannabinoid receptors in our bodies to activate our endocannabinoid system back to a homeostasis state i.e. the phytocannabinoids help our bodies regain a level of optimal health.

If the above sounds too far fetched, is it not more far fetched as to why a medicinal plant was demonized and criminalized to the extent it was in the first place?

For a scientific explanation of how the cannabinoids in cannabis can cure liver cancer (HCC), do review this and other articles.

Cannabinoids and Terpenes – The Medicinal Benefits of Cannabis

cannabinoids

The above e-book has just been released on Kindle!  It includes important information on two organic compounds found in the cannabis plant, namely cannabinoids and terpenes.  Cannabinoids are closely related “terpenophenolic”.  Terpenophenolic compounds are natural products of mixed biosynthetic origin,, specifically, they are a combination of hydrocarbon and carbonic acid molecules. Terpenophenolic compounds also contain biological activities that make them important for human health.

Terpenes are a large and diverse class of organic compounds produced by a number of plants of which many are “aromatic hydrocarbons” (sometimes called arenes).  When terpenes are chemically modified such as by oxidation, they are referred to as terpenoids.  Terpenoids are also known as isoprenoids.  Terpenes and terpenoids are the primary constituents of the essential oils of many plants including cannabis. They are what gives off the distinctive aroma of the particular strain in your medicine.

The synergistic effects of cannabinoids and terpenes offer a great deal of additional benefits which is only beginning to be investigated scientifically.  As patients become more educated on the full potential of cannabis, cannabis preparations and with the complexities in the various compounds found within cannabis, they will become more discerning in choosing their medicine which will help increase the quality of the medication available to them along with the research relating to the synergistic benefits of cannabinoids and terpenes.

This book reviews the test kits available for home use that are available and able to qualify and quantify the cannabinoids in a patient’s medical strain.  Upon using an inexpensive “Thin Layer Chromatography” (TLC) kit, the author was, at the time of testing, shocked to see cannabigerol (CBG) but no cannabidiol (CBD) in the test results, and this started a brand new intensive research into discovering just what cannabinoid(S) was responsible for curing cancer.

Since science took an overwhelming interest in studying THC, it was only recently that renewed interest rose in the other cannabinoids (of which there are 70) and very recently, terpenes.  Both are synthesized in the secretory cells inside the trichomes that are highly concentrated inside the unfertilized female flowers before they degrade or grow old.

Science is starting to understand that it is more than just THC that contains medicinal benefits, in fact the synergistic potential of the cannabinoids and terpenes is a very recent focus in science with the goal of determining exactly how this plant is able to offer so much yet is now well understood.

In addition to discussing the test kits available for testing cannabis strains, this e-book discusses the therapeutic benefits of both the cannabinoids and terpenes leaving the reader fascinated by the huge potential that this plant has to offer and which science is only beginning to unveil.

It is interesting to note how much of an effect that simply pruning the plant’s leaves as harvest approaches will unintentionally affect the plant’s  trichomes